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| Status |
Public on Jan 25, 2022 |
| Title |
The chromatin organization of a chlorarachniophyte nucleomorph genome |
| Organism |
Bigelowiella natans |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Other
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| Summary |
Nucleomoprhs are remnants of secondary endosymbiotic events between two eukaryote cells wherein the endosymbiont has retained its eukaryotic nucleus. Nucleomoprhs have evolved at least twice independently, in chlorarachniophytes and cryptophytes, yet they have converged on a remarkably similar genomic architecture, characterized by the most extreme compression and minituarization among all known eukaryotes. Previous computational studies have suggested that nucleomorph chromatin likely exhibits a number of divergent features. In this work, we provide the first maps of open chromatin, active transcription, and three-dimensional genome architecture in the nucleomorph of the chlorarachniophyte Bigelowiella natans
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| Overall design |
Hi-C, KAS-Seq, ATAC-Seq
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| Contributor(s) |
Marinov GK, Chen X, Wu T, He C, Grossman AR, Kundaje A, Greenleaf WJ |
| Citation(s) |
35232465 |
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| Submission date |
Aug 10, 2021 |
| Last update date |
Mar 30, 2022 |
| Contact name |
Georgi Kolev Marinov |
| Organization name |
STANFORD UNIVERSITY
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| Department |
Genetics
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| Street address |
279 Campus Drive West, Beckman Center, B-257A/259
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| City |
Stanford |
| State/province |
California |
| ZIP/Postal code |
94305-5101 |
| Country |
USA |
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| Platforms (1) |
| GPL30494 |
NextSeq 550 (Bigelowiella natans) |
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| Samples (5)
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| Relations |
| BioProject |
PRJNA753294 |
| SRA |
SRP331831 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE181751_RAW.tar |
870.2 Mb |
(http)(custom) |
TAR (of BIGWIG, HIC) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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