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Series GSE182758 Query DataSets for GSE182758
Status Public on Oct 03, 2023
Title eQTL mapping of fetal-like pancreatic progenitor cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary The goal of this study is to understand the effects of genetic variation on gene expression in fetal-like pancreatic progenitor cells. We generated bulk RNA-seq from 107 iPSC-derived pancreatic progenitor cells (iPSC-PPC) from iPSC lines derived from 106 individuals from the iPSCORE resource. We then conducted genome-wide expression quantitative trait loci analyses to identify genetic variants associated with gene expression and isoform usage.
Overall design This repository provides bulk RNA-seq data generated from 107 iPSC-derived pancreatic progenitor samples from 106 individuals in the iPSCORE Resource (PMID: 28410642). 102 samples were sequenced twice to obtain sufficient number of reads while five samples were sequenced once because they already had sufficient reads.
Contributor(s) Nguyen J, Frazer KA, D'Antonio M
Citation(s) 37903777
Submission date Aug 25, 2021
Last update date Nov 16, 2023
Contact name Jennifer P. Nguyen
Phone 4699880292
Organization name University of California - San Diego
Street address 9500 Gilman Dr
City La Jolla
State/province California
ZIP/Postal code 92093
Country USA
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (107)
GSM6934734 PPC147
GSM6934735 PPC047
GSM6934736 PPC153
BioProject PRJNA757719
SRA SRP334080

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE182758_RAW.tar 600.5 Mb (http)(custom) TAR (of GENOME, RESULTS)
GSE182758_sample_mapping_file.txt.gz 6.8 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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