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| Status |
Public on Nov 04, 2009 |
| Title |
Global gene expression analysis of (1) chemically reprogrammed iPS cells, and (2) chemical-treated cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of iPS cells generated with a small molecule, RepSox (RS), as well as a time-course of gene expression changes in cells treated with RS.
The former was done to verify the similarity of the iPS cells with mES cells; the latter was aimed at elucidating the mechanism of drug action in the context of reprogramming.
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| |
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| Overall design |
Total RNA obtained from iPS cells compared with mES and fibroblasts; total RNA obtained from untreated cells compared with RepSox-treated cells at various timepoints.
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| |
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| Contributor(s) |
Son EY, Ichida JK, Eggan K |
| Citation(s) |
19818703 |
| |
| Submission date |
Sep 25, 2009 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Esther Yesde Son |
| E-mail(s) |
son@fas.harvard.edu
|
| Phone |
617-496-5611
|
| Fax |
617-384-5611
|
| Organization name |
Harvard University
|
| Department |
Stem Cells and Regenerative Biology
|
| Lab |
Eggan
|
| Street address |
7 Divinity Avenue
|
| City |
Cambridge |
| State/province |
MA |
| ZIP/Postal code |
02138 |
| Country |
USA |
| |
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| Platforms (2) |
| GPL6103 |
Illumina mouseRef-8 v1.1 expression beadchip |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
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| Samples (33)
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| Relations |
| BioProject |
PRJNA119647 |
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