GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE183072 Query DataSets for GSE183072
Status Public on Apr 30, 2023
Title Gene Expression Changes after Coumestrol Stimulation of Human Trophoblast Cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Coumestrol is a potent isoflavone found in spinach and soy. To examine whether consuming large amounts of coumestrol during pregnancy affects the development of the placenta, human trophoblast cells (HTR8/Svneo) were treated with vehicle or coumestrol. Upon treatment, 3,079 genes were differentially regulated.
Overall design Human trophoblast cell lines (HTR8/Svneo) were grown up and plated into 6-well plates. Upon reaching 70% confluency, cells were treated with media containing vehicle or 65┬ÁM coumestrol for 24 hours. At the time of harvest, cells were washed with sterile PBS and then RNA was isolated for downstream microarray analysis.
Contributor(s) Caron KM, Marbrey MW
Citation(s) 37078791
Submission date Aug 31, 2021
Last update date Sep 08, 2023
Contact name Kathleen M Caron
Organization name University of North Carolin
Department Cell Biology and Physiology
Street address 111 Mason Farm Road, CB7545
City Chapel Hill
State/province NC
ZIP/Postal code 27599
Country USA
Platforms (1)
GPL23159 [Clariom_S_Human] Affymetrix Clariom S Assay, Human (Includes Pico Assay)
Samples (6)
GSM5550721 vehicle, 24 hours, biological rep1
GSM5550722 vehicle, 24 hours, biological rep2
GSM5550723 vehicle, 24 hours, biological rep3
BioProject PRJNA759118

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE183072_RAW.tar 6.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap