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Series GSE18802 Query DataSets for GSE18802
Status Public on Apr 30, 2012
Title Comparison of gene expression profiles in diploid and transformed tetraploid MEF cells
Organism Mus musculus
Experiment type Expression profiling by array
Summary We propose that abnormal DNA content in tetraploid cells can alter the gene expression profile, contributing to the cellular transformation. To test this hypothesis, we employ mRNA microarray to compare the gene expression profile in transformed tetraploid cells with that in the parent diploid cells.

Keywords: gene expression profile determination
 
Overall design Total RNA were extracted from diploid or tetraploid cells (n = 3 for each cell lines. mRNA microarray hybridization was conducted. Data were collected and analyzed.
 
Contributor(s) Wu X, Zheng L, Zhou M, Dai H, Shen B
Citation(s) 22569363
Submission date Oct 29, 2009
Last update date Mar 04, 2019
Contact name Xiwei Wu
E-mail(s) xwu@coh.org
Organization name City of Hope National Medical Center
Department Computational and Quantitative Medicine
Street address 1500 E. Duarte Rd.
City Duarte
State/province CA
ZIP/Postal code 91010
Country USA
 
Platforms (1)
GPL6246 [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Samples (6)
GSM466402 tetraploidy (174_1)
GSM466403 tetraploidy (174_2)
GSM466404 tetraploidy (174_3)
This SubSeries is part of SuperSeries:
GSE18815 Comparison of diploid and transformed tetraploid MEF cells: gene expression and DNA methylation profiling
Relations
BioProject PRJNA123855

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE18802_RAW.tar 25.6 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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