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Status |
Public on Jul 15, 2022 |
Title |
The oxidoreductase CLIC4 is required to maintain mitochondrial function and resistance to exogenous oxidants in breast cancer cells. |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
We report the different transcriptom of 6DT1 (murine mammary cancer cell line) wildtype cells or CLIC4-KO (by CRISPR cas9) untreated or treated 1uM H2O2 for 24 hours.
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Overall design |
6DT1 transduced with lentivirus to express CLIC4 (lenti) or with lentivirus to express an empty vector (empty) cells were untreated or treated with 1uM H2O2 for 24 hours.
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Contributor(s) |
Al Khamici H, Sanchez VC, Yan H, Cataisson C, Michalowski A, Yang HH, Li L, Lee MP, Huang J, Yuspa SH |
Citation(s) |
35863434 |
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Submission date |
Nov 14, 2021 |
Last update date |
Sep 14, 2022 |
Contact name |
Howard Yang |
E-mail(s) |
yanghow@mail.nih.gov
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Phone |
2402765257
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Organization name |
NCI
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Street address |
9609 Medical Center Dr.
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City |
Rockville |
State/province |
MD |
ZIP/Postal code |
20850 |
Country |
USA |
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Platforms (1) |
GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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Samples (16)
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Relations |
BioProject |
PRJNA780307 |
SRA |
SRP346019 |