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| Status |
Public on Jul 26, 2022 |
| Title |
The RNA sequencing analysis of nasopharyngeal carcinoma (NPC) cell line S18 upon circIPO7 knockdown |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The development of therapeutic resistance and metastatic dissemination takes place in 20-30% patients with nasopharyngeal carcinoma (NPC), resulting in poor survival. Hence, a better understanding of the underlying molecular mechanisms will help improve clinical outcome. We have identified a novel circRNA, circIPO7, as a promoter of metastasis and cisplatin chemoresistance in NPC cells. High-throughput RNA sequencing analysis was performed in the human nasopharyngeal carcinoma cell line S18 after transfection with control siRNA or circIPO7 siRNA.
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| Overall design |
High-throughput RNA sequencing analysis was performed in the human nasopharyngeal carcinoma cell line S18 after transfection with control siRNA or circIPO7 siRNA.
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| Contributor(s) |
Hong XH, Ma J, Li YQ |
| Citation(s) |
35917517 |
| |
| Submission date |
Nov 23, 2021 |
| Last update date |
Oct 26, 2022 |
| Contact name |
Yingqin Li |
| E-mail(s) |
liyingq@sysucc.org.cn
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| Organization name |
Sun Yat-sen University Cancer Center
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| Lab |
State Key Laboratory of Oncology in South China
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| Street address |
Room 927, Building 2, No. 651 Road Dong Feng East
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| City |
Guangzhou |
| State/province |
Guangdong |
| ZIP/Postal code |
510060 |
| Country |
China |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE189459 |
CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Regulating YBX1 Nuclear Localization |
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| Relations |
| BioProject |
PRJNA783044 |
| SRA |
SRP347501 |
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