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| Status |
Public on Aug 15, 2013 |
| Title |
S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133_Plus_2] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
We and others have shown that S100P is highly upregulated during the progression of pancreatic cancer. We used microarrays to look at the target genes regulated by S100P in the pancreatic cancer cell line Panc1.
Keywords: Gene overexpression
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| Overall design |
We generated stable cell lines by introducing control vector pcDNA3.1/V5-His or S100P-overexpressing vector pcDNA3.1/S100P-V5-His into the pancreatic cancer cell line Panc1, single cell clones were then isolated. RNA was extracted and hybridized on Affymetrix microarrays. We looked for new target genes regulated by S100P.
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| Contributor(s) |
Barry S, Chelala C, Crnogorac-Jurcevic T |
| Citation(s) |
23007696 |
| |
| Submission date |
Dec 02, 2009 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Claude Chelala |
| E-mail(s) |
c.chelala@qmul.ac.uk
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| Organization name |
Barts & The London School of Medicine (QMUL)
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| Department |
Institute of Cancer
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| Lab |
Centre for Molecular Oncology & Imaging
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| Street address |
Charterhouse square
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| City |
London |
| State/province |
London |
| ZIP/Postal code |
EC1M6BQ |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (7)
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| This SubSeries is part of SuperSeries: |
| GSE19281 |
S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells |
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| Relations |
| BioProject |
PRJNA123889 |
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