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Series GSE193853 Query DataSets for GSE193853
Status Public on Jun 30, 2023
Title RNA-seq of small cell lung cancer [Small RNA-Seq]
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary We used CCK-8 experiment to determine the chemotherapy tolerance of small cell lung cancer cells, from which we found chemotherapy-sensitive cells (H446) and chemotherapy-tolerant cells (SHP77).By RNA-SEQ, we found 99 miRNAs with abnormal expression associated with chemotherapy tolerance, including 69 up-regulated miRNAs and 30 down-regulated miRNAs. Several miRNAs related to chemotherapy tolerance of small cell lung cancer were found through qRT-PCR verification, which helped us to further clarify the mechanism of chemotherapy tolerance of small cell lung cancer.
Overall design Small RNA profiles of small cell lung cancer
Contributor(s) Chao F, Li M
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Submission date Jan 17, 2022
Last update date Jun 30, 2023
Contact name fengmei chao
Organization name Anhui Provincial Cancer Hospital
Street address East Huanhu road
City Hefei
State/province Anhui
ZIP/Postal code 230031
Country China
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (2)
GSM5822679 H446 (sRNA-Seq)
GSM5822680 SHP77 (sRNA-Seq)
This SubSeries is part of SuperSeries:
GSE193854 RNA-seq of small cell lung cancer
BioProject PRJNA798099

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE193853_RAW.tar 30.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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