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Series GSE195567 Query DataSets for GSE195567
Status Public on Feb 04, 2022
Title DNA methylation array analysis of high-grade gliomas with pleomorphic and pseudopapillary features
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Genomewide DNA methylation array profiling of 23 previously unpublished CNS tumors resolved into a new entity, high-grade glioma with pleomorphic and pseudopapillary features (HPAP). Tumors demonstrate a variety of histologic diagnoses including glioblastoma (GBM), pleomorphic xanthoastrocytoma (PXA), anaplastic ependymoma, and polymorphous low-grade neuroepithelial tumor of the young (PLNTY). The Illumina Infinium EPIC 850k Human DNA Methylation Beadchip was used to obtain DNA methylation profiles across approximately 850,000 CpG sites of genomic DNA extracted from formalin-fixed, paraffin-embedded tumor tissue.
Overall design Bisulfite converted genomic DNA extracted from 23 tumor samples was hybridized to Illumina Infinium EPIC Human DNA Methylation Beadchips
Contributor(s) Pratt D
Citation(s) 35103816
Submission date Jan 27, 2022
Last update date Feb 12, 2022
Contact name Drew Pratt
Organization name National Institutes of Health
Department Laboratory of Pathology
Street address 10 Center Drive, Building 10, Room 2S235
City Bethesda
State/province Maryland
ZIP/Postal code 20892
Country USA
Platforms (1)
GPL21145 Infinium MethylationEPIC
Samples (23)
GSM5840598 HPAP Case 3
GSM5840599 HPAP Case 9
GSM5840600 HPAP Case 10
BioProject PRJNA801252

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE195567_RAW.tar 485.9 Mb (http)(custom) TAR (of IDAT)
Processed data included within Sample table

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