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Series GSE19648 Query DataSets for GSE19648
Status Public on Sep 30, 2010
Title Murine Histone Methyltransferase Mll5, is involved in Male Gametogenesis
Organism Mus musculus
Experiment type Expression profiling by array
Summary Male mice but not female Mll5 -/- mice are infertile. This study showed that post-meiotic spermatogenic maturation is impaired in Mll5 -/- mice. In order to investigate the role of Mll5 in spermatogenesis, a transcriptome analysis of whole testes from Mll5 knock out and wildtype mice was performed.
Affymetrix Mouse Exon chips were hybridized with testes material from three individual male mice from each wild-type or Mll5 -/- genotype, in order to identify gene regulation differences attributed to the loss of Mll5.
 
Overall design One-way ANOVA: wildtype vs. Mll5-/-
 
Contributor(s) Yap DB, Walker DC, McKinney S, Turashvili G, Mooslehner-Allen K, de Algara TR, Prentice LM, Fee J, d'Anglemont de Tassigny X, Colledge WH, Aparicio SA
Citation(s) 22069496
Submission date Dec 24, 2009
Last update date Mar 03, 2017
Contact name Steven McKinney
E-mail(s) smckinney@bccrc.ca
Phone 604-675-8000
Organization name British Columbia Cancer Agency
Department Molecular Oncology
Lab Samuel Aparicio
Street address 675 West 10th Ave
City Vancouver
State/province BC
ZIP/Postal code V5Z 1L3
Country Canada
 
Platforms (1)
GPL6193 [MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [probe set (exon) version]
Samples (6)
GSM490126 testis-wildtype#1-rep1
GSM490127 testis-wildtype#2-rep2
GSM490128 testis-wildtype#3-rep3
Relations
BioProject PRJNA122541

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE19648_ArrayAssist_Exon_Matrix.txt.gz 22.4 Kb (ftp)(http) TXT
GSE19648_ArrayAssist_Gene_Matrix.txt.gz 286.9 Kb (ftp)(http) TXT
GSE19648_RAW.tar 186.1 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data are available on Series record
Processed data provided as supplementary file

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