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| Status |
Public on Feb 02, 2023 |
| Title |
Wound memory of epidermal stem cells [scRNAseq L1-aged] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Wound priming in epidermal Lrig1 stem cell progeny leads to a more efficient response to future injuries. To understand if primed progenitors maintain during aging the transcriptional program acquired during wound healing in young age, we performed single cell RNA-Seq of Lrig1 stem cell progeny 40 weeks after injury.
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| Overall design |
Single cell RNA-seq transcriptome profiling of epidermal Lrig1 stem cell progenies. After genetical labelling through tamoxifen application, tomato positive epidermal cells were sorted from repaired and age control skin.
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| Contributor(s) |
Levra Levron C, Watanabe M, Proserpio V, Piacenti G, Lauria A, Kaltenbach S, Nohara T, Anselmi F, Duval C, Donna D, Baev D, Natsuga K, Hagai T, Oliviero S, Giacomo D |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Feb 28, 2022 |
| Last update date |
Feb 02, 2023 |
| Contact name |
Andrea Lauria |
| E-mail(s) |
andrea.lauria@unito.it
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| Organization name |
University of Turin
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| Department |
Life Sciences and Systems Biology
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| Lab |
Functional Genomics, Epigenomics - S. Oliviero
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| Street address |
Via Accademia Albertina, 13
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| City |
Turin |
| ZIP/Postal code |
10123 |
| Country |
Italy |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (310)
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| This SubSeries is part of SuperSeries: |
| GSE197590 |
Wound memory of epidermal stem cells |
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| Relations |
| BioProject |
PRJNA811146 |
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