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Series GSE198419 Query DataSets for GSE198419
Status Public on Mar 21, 2023
Title Transcriptome changes in 22Rv1 and MCF7 cells after treatment with NONO ligands and controls
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary RNA-Sequencing to determine transcriptome changes in 22Rv1 and MCF7 cells after treatment with NONO ligands and controls. NONO KO (sgNONO) or control (sgControl) cells were treated.
 
Overall design sgControl or sgNONO 22Rv1 or MCF7 cells were treated in biological triplicate with DMSO (0.04%) or SKBG-1 (R) or SKBG-1 (S) (20µM and 5µM in 22Rv1 and MCF7 cells, respectively) for 4 hours prior to RNA-sequencing.
Web link https://pubmed.ncbi.nlm.nih.gov/36864190/
 
Contributor(s) Kathman SG, Cravatt BF, Lindsey GL
Citation(s) 36864190
Submission date Mar 11, 2022
Last update date Jun 20, 2023
Contact name Garrett Lee Lindsey
E-mail(s) glindsey@scripps.edu
Phone 7608518160
Organization name Scripps Research
Department Chemistry
Lab Cravatt
Street address 10650 N Torrey Pines Rd
City La Jolla
State/province CA
ZIP/Postal code 92037
Country USA
 
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (36)
GSM5946440 Total_RNAseq_22Rv1_sgControl_4hours_DMSO_Replicate1
GSM5946441 Total_RNAseq_22Rv1_sgControl_4hours_DMSO_Replicate2
GSM5946442 Total_RNAseq_22Rv1_sgControl_4hours_DMSO_Replicate3
This SubSeries is part of SuperSeries:
GSE222217 Remodeling oncogenic transcriptomes by small molecules targeting NONO
Relations
BioProject PRJNA815049

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Supplementary file Size Download File type/resource
GSE198419_22Rv1_rMATS_result.xlsx 113.4 Mb (ftp)(http) XLSX
GSE198419_22Rv1_raw_gene_counts.csv.gz 1.6 Mb (ftp)(http) CSV
GSE198419_MCF7_raw_gene_counts.csv.gz 1.4 Mb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record
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