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Series GSE200790 Query DataSets for GSE200790
Status Public on May 29, 2024
Title Transcriptomes analyses of gastric cancer HGC-27 cell line treated with lactate
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Lactate is a major metabolite of tumor cell as a result of Warburg effect. Yet it remains elusive whether and how intracellular lactate may ever drive tumor cell proliferation. To investigat the role of lactate in proliferating cancer cells, we treated HGC27 cells with lactate and then sent for RNA-sequencing analysis.
Overall design Total RNA was extracted from HGC27 cells cultured in glucose-free medium with or without exogenous 25mM lactate in duplicate and then sent for transcriptomes analysis.
Contributor(s) Ju J, Jiao S, Tang Y
Citation(s) 38512451
Submission date Apr 14, 2022
Last update date May 29, 2024
Contact name junyi ju
Organization name Shanghai Tenth People’s Hospital
Street address 301 middle yanchang road
City shanghai
ZIP/Postal code 200072
Country China
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (4)
GSM6043799 HGC27 cell, noglu, rep1
GSM6043800 HGC27 cell, noglu, rep2
GSM6043801 HGC27 cell, lactate, rep1
BioProject PRJNA826822

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Supplementary file Size Download File type/resource
GSE200790_noglu_vs_25lac.deseq.xlsx 2.1 Mb (ftp)(http) XLSX
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