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Series GSE201648 Query DataSets for GSE201648
Status Public on Apr 29, 2022
Title RNA-seq analysis of Arabidopsis root with MBZ treatment
Organism Arabidopsis thaliana
Experiment type Expression profiling by high throughput sequencing
Summary we reported the identification of a small molecule, Mebendazole (MBZ) that modulates GSA in Arabidopsis thaliana roots. To identify pathways immediately response to MBZ, we performed an mRNA-seq using roots of 14-days-old Arabidopsis grown on DMSO plates treated with DMSO or 10 µM MBZ for 4 hours. Differenetial expressed genes between DMSO and MBZ_4h treatments were analyzed. It has 8 samples in total, with 4 replicates for each treatment.
 
Overall design 14 d old seedlings of Col-0 on DMSO plates were transferred to DMSO plates with 10 µM mebendazole or DMSO. After treatment for 4 h, root tissues were collected for RNA extraction and sequencing. Every treatment have 4 replicates.
 
Contributor(s) Busch W, He W, Zhang L
Citation(s) 38358890
Submission date Apr 26, 2022
Last update date Apr 02, 2024
Contact name Ling Zhang
E-mail(s) linzhang@salk.edu
Organization name Salk Institute for Biological Studies
Street address 10010 N Torrey Pines Rd
City La Jolla
State/province CA
ZIP/Postal code 92037
Country USA
 
Platforms (1)
GPL19580 Illumina NextSeq 500 (Arabidopsis thaliana)
Samples (8)
GSM6069051 Root, DMSO, rep1
GSM6069052 Root, DMSO, rep2
GSM6069053 Root, DMSO, rep3
Relations
BioProject PRJNA832481

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE201648_gene_RPKM_matrix.txt.gz 1.2 Mb (ftp)(http) TXT
GSE201648_raw_gene_counts_matrix.txt.gz 447.9 Kb (ftp)(http) TXT
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