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Series GSE202231 Query DataSets for GSE202231
Status Public on Nov 01, 2022
Title RNA-Seq analysis of SK-N-BE(2) neuroblastoma cells after ARID1A and ARID1B silencing for BAF complex disruption
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary In order to determine the transcriptomic network under the control of BAF chromatin remodeling complex in neuroblastoma cells, we performed RNA-Seq analysis on a neuroblastoma cell lines to detect those transcriptionally modulated genes after the disruption of this complex through silencing of its key structural subunits ARID1A and ARID1B.
 
Overall design SK-N-BE(2) cells were transduced with lentiviral particles carrying shRNA for ARID1A and ARID1B silencing and 72 h later RNA was extracted in biological triplicates for RNA-Seq analysis.
 
Contributor(s) Jiménez C, Segura MF
Citation(s) 36057593
Submission date May 04, 2022
Last update date Nov 01, 2022
Contact name Carlos Jimenez
E-mail(s) carlos.jimenez@vhir.org
Phone +34 93 274 6873
Organization name Vall d'Hebron Institut de Recerca
Department Pediatric Oncology
Lab Neural Tumors
Street address Pg. Vall dHebron 119-129, Edificio Collserola, lab 207
City Barcelona
State/province Barcelona
ZIP/Postal code 08035
Country Spain
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (21)
GSM6106745 SK-N-BE(2) Control rep1
GSM6106746 SK-N-BE(2) Control rep2
GSM6106747 SK-N-BE(2) Control rep3
Relations
BioProject PRJNA835096

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE202231_Gene_expression_rawdata.txt.gz 2.0 Mb (ftp)(http) TXT
GSE202231_shARID1A_B_vs_control_results.txt.gz 2.3 Mb (ftp)(http) TXT
GSE202231_shARID1A_vs_control_results.txt.gz 2.3 Mb (ftp)(http) TXT
GSE202231_shARID1B_vs_control_results.txt.gz 2.3 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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