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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Sep 21, 2023 |
| Title |
Effect of Creb1 KD on TVA dependent CD8+ T cell activation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate the role of Creb1 in TVA dependent CD8+ T cell activation, we knocked down Creb1 of mouse CD8+ T cells with siRNAs then treated with DMSO or TVA
We then performed gene expression profiling analysis using data obtained from RNA-seq.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for 4 groups: CON,TVA,siCREB,siCREBTVA
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| Contributor(s) |
Fan H, Dong L, Su R, Gao X, Chen J |
| Citation(s) |
37993715 |
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| Submission date |
May 05, 2022 |
| Last update date |
Dec 07, 2023 |
| Contact name |
fan hao |
| E-mail(s) |
haofan@uchicago.edu
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| Organization name |
University of Chicago
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| Street address |
5801 S Ellis Ave
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| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60637 |
| Country |
USA |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (12)
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| GSM6107614 |
CD8+ T cells, siNTC, TVA, 1 |
| GSM6107616 |
CD8+ T cells, siNTC, TVA, 2 |
| GSM6107618 |
CD8+ T cells, siNTC, TVA, 3 |
| GSM6107620 |
CD8+ T cells, siCreb1, DMSO, 1 |
| GSM6107622 |
CD8+ T cells, siCreb1, DMSO, 2 |
| GSM6107624 |
CD8+ T cells, siCreb1, DMSO, 3 |
| GSM6107626 |
CD8+ T cells, siCreb1, TVA, 1 |
| GSM6107628 |
CD8+ T cells, siCreb1, TVA, 2 |
| GSM6107630 |
CD8+ T cells, siCreb1, TVA, 3 |
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| This SubSeries is part of SuperSeries: |
| GSE202340 |
Dietary trans-vaccenic acid promotes anti-tumor immunity |
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| Relations |
| BioProject |
PRJNA835324 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE202274_RAW.tar |
24.2 Mb |
(http)(custom) |
TAR (of TXT) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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