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| Status |
Public on Jul 07, 2022 |
| Title |
The differences in miRNA expression with miRNA microarrays of two-dimensional (2D)- and three-dimensional (3D)-SNP cells |
| Organism |
Canis lupus familiaris |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
Canine mammary gland tumors can be used as predictive models for human breast cancer. There are several types of microRNAs common in human breast cancer and canine mammary gland tumors. The functions of microRNAs in canine mammary gland tumors are not well understood. In the present study, we compared the characterization of microRNA expression in two-dimensional and three-dimensional canine mammary gland tumor cell models.
The expression of microRNA-210 in the three-dimensional-SNP cells was 10.19 times higher than that in the two-dimensional-SNP cells.
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| Overall design |
We evaluated the differences between 2D- and 3D-cultured canine mammary gland tumors (2D-SNP and 3D-SNP) by assessing miRNA expression levels.
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| Contributor(s) |
Osaki T |
| Citation(s) |
36811028 |
| |
| Submission date |
May 19, 2022 |
| Last update date |
Sep 01, 2023 |
| Contact name |
Satoshi Kondo |
| Organization name |
Toray Industries,Inc.
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| Street address |
10-1 tebiro 6-chome
|
| City |
Kamakura |
| State/province |
Kanagawa |
| ZIP/Postal code |
248-8555 |
| Country |
Japan |
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| Platforms (1) |
| GPL25866 |
3D-Gene 4animal Dog miRNA V20_1.0.0 |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA839780 |
