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Series GSE205457 Query DataSets for GSE205457
Status Public on Feb 07, 2023
Title Expression data from chordoma and notochord (RNA-Seq)
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Chordoma is a rare malignant tumor thought to originate from embryonic notochord. However, no molecular comparison of chordoma and notochord has been performed to date, leaving the identities of dysregulated pathways unclear. Absence of a molecular description of a control tissue clouds our understanding of chordoma. Thus, we conducted an unbiased comparison of chordoma and notochord using gene expression profiling to clarify chordoma’s tissue of origin and identify novel drug targets
 
Overall design RNA was extracted from fresh chordoma tumors after surgical resection using Trizol. RNA from notochord was obtained via laser capture microdissection.
 
Contributor(s) Halvorsen SC
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Submission date Jun 03, 2022
Last update date Feb 09, 2023
Contact name Stefan Halvorsen
E-mail(s) shalvorsen@ccib.mgh.harvard.edu
Organization name Massachusetts General Hospital
Department Center for Computational and Integrative Biology
Lab Seed Lab
Street address 185 Cambridge Street
City Boston
State/province MA
ZIP/Postal code 02114
Country USA
 
Platforms (1)
GPL9115 Illumina Genome Analyzer II (Homo sapiens)
Samples (11)
GSM6213097 Chordoma Sample 10
GSM6213098 Chordoma Sample 11
GSM6213099 Chordoma Sample 1
This SubSeries is part of SuperSeries:
GSE205458 Expression data from chordoma and notochord
Relations
BioProject PRJNA845775

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE205457_RAW.tar 3.1 Mb (http)(custom) TAR (of TAB)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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