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Series GSE206804 Query DataSets for GSE206804
Status Public on Jun 07, 2023
Title Comparative RNA sequencing of the jejuna of two lines of chickens divergently selected for antibody response to sheep red blood cells, with and without antigen exposure
Organism Gallus gallus
Experiment type Expression profiling by high throughput sequencing
Summary Two lines of White Leghorn chickens have been continuously divergently selected for high (HAS) or low (LAS) 5 day post injection antibody titer to injection with sheep red blood cells (SRBC) for over 40 generations. Much remains to be understood about their antibody response phenotypes, therfore we chose to sequence the transcriptomes of the jejunum from individuals of the two lines which had (HASI/LASI) and had not (HASN/LASN) been injected with SRBC to examine differences in gene expression related to divergent selection and antibody response.
Overall design Investigate differential jejunum gene expression from 24 chickens total: 6 each HASN, LASN, HASI, and LASI, to compare differences between lines with regard to genetic selection (HAS vs LAS) and within lines in response to antigen exposure (I vs N)
Contributor(s) Nolin S, Ashwell C, Edens F, Siegel P
Citation(s) 37244088
Submission date Jun 23, 2022
Last update date Jun 07, 2023
Contact name Shelly Jones Nolin
Phone 9195155537
Organization name NC State University
Department Prestage Dept of Poultry Science
Lab Poultry Genomics
Street address 2711 Founders Dr
City Raleigh
State/province NC
ZIP/Postal code 27695
Country USA
Platforms (1)
GPL19005 Illumina HiSeq 2500 (Gallus gallus)
Samples (24)
GSM6263879 HAS_Injected-1
GSM6263880 HAS_Injected-2
GSM6263881 HAS_Injected-3
BioProject PRJNA852232

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE206804_HAS_LAS_RNASeq.txt.gz 2.2 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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