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Status |
Public on Sep 22, 2023 |
Title |
Epithelial Gab1 calibrates RIPK3-dependent necroptosis to prevent intestinal inflammation |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
We report that epithelial-Gab1 deficiency in mice facilitates inflammatory cell infiltration and aggravates colonic inflammation in colitis microenvironment
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Overall design |
Relative mRNA level in colon tissue obtained from Gab1IEC KO and Gab1fl/fl mice with a 7-day DSS treatment
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Contributor(s) |
Xu J, Zhang X |
Citation(s) |
36795486 |
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Submission date |
Jun 24, 2022 |
Last update date |
Sep 22, 2023 |
Contact name |
Jiaqi Xu |
E-mail(s) |
xujiaqi@zju.edu.cn
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Organization name |
Sir Run Run Shaw hospital, Zhejiang University School of Medicine
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Street address |
866 Yuhangtang Road, Hangzhou, Zhejiang, China
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City |
Hangzhou |
ZIP/Postal code |
310058 |
Country |
China |
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Platforms (1) |
GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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Samples (6)
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Relations |
BioProject |
PRJNA852539 |