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Series GSE207861 Query DataSets for GSE207861
Status Public on Jun 07, 2023
Title Sex-based comparison of CD4+ T cell DNA methylation patterns in SLE reveals pro-inflammatory epigenetic changes in men
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Male patients with systemic lupus erythematosus (SLE) experience severe disease compared to female patients, despite the disease being more prevalent in females. For the time, we compared genome-wide differential methylation in CD4+ T cells between male (n=12) and female (n=10) SLE patients.
Overall design Illumina Infinium MethylationEPIC array of genomic DNA from CD4+ T cells extracted from peripheral blood mononuclear cells of 12 male SLE patients and 10 female SLE patients.
Contributor(s) Ali M, Coit P, Sawalha AH
Citation(s) 36075396
Submission date Jul 10, 2022
Last update date Jun 08, 2023
Contact name Amr H Sawalha
Organization name University of Pittsburgh
Street address 4401 Penn Avenue
City Pittsburgh
State/province PA
ZIP/Postal code 15224
Country USA
Platforms (1)
GPL21145 Infinium MethylationEPIC
Samples (22)
GSM6321396 CD4_SLE_P1_F
GSM6321397 CD4_SLE_P2_F
GSM6321398 CD4_SLE_P3_M
BioProject PRJNA857452

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE207861_Processed_Beta_Values_for_Each_Patient.xlsx 227.5 Mb (ftp)(http) XLSX
GSE207861_RAW.tar 472.3 Mb (http)(custom) TAR (of IDAT)
GSE207861_processed_data.txt.gz 19.6 Mb (ftp)(http) TXT
Processed data included within Sample table
Processed data are available on Series record

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