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Status |
Public on Jun 07, 2023 |
Title |
Cxxc finger protein 1 maintains homeostasis and function of intestinal group 3 innate lymphoid cells with aging |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
To investigate the role of aging in the regulation of ILC3 development and function, we used aged mice and carried out single-cell RNA sequencing (BD Rhapsody) on aged gut ILC3s.
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Overall design |
ILC3s from 18-months-old male C57BL/6 mice were isolated from the small intestine and analyzed by single-cell RNA sequencing technology (BD Rhapsody).
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Web link |
https://www.nature.com/articles/s43587-023-00453-7
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Contributor(s) |
Shen X, Gao X, Wang L |
Citation(s) |
37429951 |
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Submission date |
Jul 21, 2022 |
Last update date |
Sep 07, 2023 |
Contact name |
lie wang |
E-mail(s) |
wanglie@zju.edu.cn
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Organization name |
zhejiang universiry
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Department |
immunology
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Street address |
Zijingang Campus, Zhejiang Universityļ¼Yuhangtang Road 866
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City |
hangzhou |
State/province |
zhejiang |
ZIP/Postal code |
310058 |
Country |
China |
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Platforms (1) |
GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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Samples (2) |
GSM6365793 |
Group 3 innate lymphoid cell, aged gut ILC3s rep1, scRNAseq |
GSM6365794 |
Group 3 innate lymphoid cell, aged gut ILC3s rep2, scRNAseq |
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Relations |
BioProject |
PRJNA860836 |