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Series GSE209933 Query DataSets for GSE209933
Status Public on Jun 14, 2024
Title A tagged histone variant exploits cancer-specific pathway in human cells
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Little is knownThe use of tags is ubiquitous in scientific research, has allowed researchers the capability to make great strides in scientific discoveries that have left lasting impact in many disciplines. Here, we investigate the aberrant functional roles associated with C-terminally TAP-tagged CENP-A (CpA-TAP) when compared to centromeric native CENP-A (CpA).
 
Overall design ChIPseq of native CpA or CpA-TAP in control or transfected HeLa cells, in a DAXX knock-out (KO) cell line, and double DAXX KO + HIRA knock-down. ChIPseq was replicated for GFP-CpA expressing HeLa cells.
 
Contributor(s) Bui M, Baek S, Dalal Y
Citation(s) 38825690
Submission date Jul 27, 2022
Last update date Jun 15, 2024
Contact name Songjoon Baek
Organization name NCI / NIH
Department CCR
Lab LRBGE
Street address 41 Library Drive
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
 
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (41)
GSM6410779 Beads only IP
GSM6410780 Input of ChIP_nCpA_HeLaCont_01
GSM6410781 nCpA ChIP in HeLaCont rep #1
Relations
BioProject PRJNA862973

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE209933_RAW.tar 6.7 Mb (http)(custom) TAR (of NARROWPEAK)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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