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Series GSE209970 Query DataSets for GSE209970
Status Public on Dec 01, 2023
Title Microglia care for neurons through tunneling nanotubes [Dataset 1 Neurons mRNA-seq]
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We report the transfer of alpha-s-ynuclein aggregates from neurons to microglia and examined transcriptomic changes following protein extraction. By obtaining RNA samples, we performed differential expression analysis and generated gene ontology enrichment and network analysis.
Overall design mRNA sequencing of Neurons from mice treated with and without aSyn cocultured in the presence of microglia
Contributor(s) Scheiblich H, Eikens F, Wischhof L, Opitz S, Jüngling K, Cserép C, Schmidt SV, Bellande T, Pósfai B, Geck C, Spitzer J, Odainic A, Schwartz S, Di Monte DA, Bano D, Dénes Á, Latz E, Melki R, Pape H, Heneka MT
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Submission date Jul 28, 2022
Last update date Dec 01, 2023
Contact name Susanne Schmidt
Phone +4922828712102
Organization name University Hospital Bonn
Department Institute of Clin. Chemistry and Clin. Pharmacology
Lab Immune Monitoring & Genomics
Street address Venusberg-Campus 1
City Bonn
ZIP/Postal code 53127
Country Germany
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (16)
GSM6411905 Neurons_single_aSyn [DE39NGSUKBR117811]
GSM6411906 Neurons_single_aSyn [DE44NGSUKBR117818]
GSM6411907 Neurons_single_aSyn [DE49NGSUKBR117825]
This SubSeries is part of SuperSeries:
GSE209972 Microglia care for neurons through tunneling nanotubes
BioProject PRJNA863252

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MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE209970_DEseq2_normalized_data.txt.gz 394.2 Kb (ftp)(http) TXT
GSE209970_raw_gene_counts.txt.gz 397.5 Kb (ftp)(http) TXT
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Processed data are available on Series record

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