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Series GSE210004 Query DataSets for GSE210004
Status Public on Apr 19, 2024
Title Activin A and CCR2 regulate the function of macrophages in testicular fibrosis caused by experimental autoimmune orchitis
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Treatment of bone marrow-derived macrophages with activin A in vitro increased the expression of Ccr2, Fn1, Cxcr4, and Mmp2 and these effects were abolished by follistatin.
 
Overall design In order to investigate whether activin A contributes to inflammatory and fibrotic responses by regulating macrophages, mouse BMDMs were stimulated with activin A in vitro. FST288 was used as an antagonist of activin A.
 
Contributor(s) Fijak M, Peng W, Guenther S
Citation(s) 36434305
Submission date Jul 28, 2022
Last update date Apr 19, 2024
Contact name Stefan G√ľnther
E-mail(s) stefan.guenther@mpi-bn.mpg.de
Organization name MPI for heart and lung research
Street address ludwigtr. 43
City bad nauheim
ZIP/Postal code 61231
Country Germany
 
Platforms (1)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
Samples (12)
GSM6413325 BMDM, untreated, day 6 1
GSM6413326 BMDM, untreated, day 6 2
GSM6413327 BMDM, untreated, day 6 3
Relations
BioProject PRJNA863301

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE210004_counts.matrix.norm_anno.txt.gz 9.9 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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