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Status |
Public on Sep 03, 2023 |
Title |
Tryptophan as a miR team organizer prevents colon cancer liver metastasis [small intestine] |
Platform organism |
synthetic construct |
Sample organism |
Mus musculus |
Experiment type |
Non-coding RNA profiling by array
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Summary |
Tryptophan treatment play a significant role in miR expression. We have characterized the miR expression network through miR-on-chip profiling of the mouse treated with or without tryptophan. In this dataset, we include the expression data from mouse small intestine and colon tissue treated with or without tryptophan.
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Overall design |
C57BL/6 mice are randomly devided into two groups. Each group of mice (n=8) were respectively fed with Trp depleted diet (TrpD, 0% tryptophan, w/w) or a paired diet (PD, 1.2% tryptophan, w/w). Mice tissue were dissected and pooled as two samples for each treatment.
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Contributor(s) |
Fangyi X, Sabine W |
Citation missing |
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Submission date |
Sep 02, 2022 |
Last update date |
Sep 03, 2023 |
Contact name |
Fangyi Xu |
E-mail(s) |
xufangyi4527@gmail.com
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Phone |
3462400801
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Organization name |
University of Louisville
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Department |
BCC cancer center
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Lab |
Zhang
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Street address |
505 S Hancock street
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City |
Louisville |
State/province |
Kentucky |
ZIP/Postal code |
40202 |
Country |
USA |
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Platforms (1) |
GPL21572 |
[miRNA-4] Affymetrix Multispecies miRNA-4 Array [ProbeSet ID version] |
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Samples (4)
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GSM6538358 |
Small intestine from mice treated with TrpD [HZ_B6_TrpD_SI_Tis_1] |
GSM6538359 |
Small intestine from mice treated with TrpD [HZ_B6_TrpD_SI_Tis_2] |
GSM6538360 |
Small intestine from mice treated with PD [HZ_B6_PD_SI_Tis_1] |
GSM6538361 |
Small intestine from mice treated with PD [HZ_B6_PD_SI_Tis_2] |
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Relations |
BioProject |
PRJNA876251 |