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Series GSE21323 Query DataSets for GSE21323
Status Public on Oct 07, 2010
Title Protein arginine methyltransferase AtPRMT5 is involved in pre-mRNA splicing in Arabidopsis thaliana
Organism Arabidopsis thaliana
Experiment type Expression profiling by high throughput sequencing
Summary In this study, we analyzed the Arabidopsis homologue of PRMT5, AtPRMT5’s function in RNA processing. RNA-seq analyses revealed that AtPRMT5 is involved in a subset of pre-mRNA splicing. Several RNA processing factors involved in regulating flowering time were validated that the corresponding intron retention surely exists in atprmt5 mutants. AtSm proteins can also be methylated by AtPRMT5 in vitro and in vivo, which may be the reasons for the pre-mRNA splicing defects in atprmt5.

Contributed by The Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences
 
Overall design Investigate the role of AtPRMT5 in pre-mRNA splicing
 
Contributor(s) Deng X, Gu L, Liu C, Lu T, Lu F, Lu Z, Cui P, Pei Y, Wang B, Hu S, Cao X
Citation(s) 20956294
Submission date Apr 13, 2010
Last update date May 15, 2019
Contact name xiaofeng cao
E-mail(s) xfcao@genetics.ac.cn
Phone 86-10-64869203
Organization name Institute of Genetics and Developmental Biology
Department State Key Laboratory of Plant Genomics
Street address West Lincui Road, Chaoyang District
City Beijing
ZIP/Postal code 100101
Country China
 
Platforms (1)
GPL10272 AB SOLiD System 2.0 (Arabidopsis thaliana)
Samples (2)
GSM532869 Col_RNASeq_SOLiD
GSM532870 prmt5_RNASeq_SOLiD
Relations
SRA SRP002301
BioProject PRJNA126167

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE21323_RAW.tar 69.0 Mb (http)(custom) TAR (of BEDGRAPH)
SRA Run SelectorHelp
Processed data provided as supplementary file
Raw data are available in SRA

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