GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE213494 Query DataSets for GSE213494
Status Public on Nov 27, 2023
Title Prolonged sleep deprivation induces cytokine storm-like syndrome in mammals [RNA-Seq]
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Sleep is deeply involved in neuroimmune regulation, while the mechanism is yet to be elucidated. Experimental manipulation of sleep duration provides a reliable measure for evaluating how sleep regulates innate immunity. Here we report a modified sleep deprivation paradigm (SD) that can constantly awaken the mice with more than 95% efficiency, and investigate the effects of prolonged sleep deprivation on mice's immune systems.
Overall design Blood leukocytes were isolated from the mice under control (Con), sleep deprivation(SD), or a previously reported sleep restriction method (SASD) condition after different time points to investigate the transcriptome alteration
Contributor(s) Lin K, Sang D, Zhang E
Citation(s) 38016470
Submission date Sep 16, 2022
Last update date Nov 30, 2023
Contact name Erquan Zhang
Organization name National Institute of Biological Sciences, Beijing
Lab ErquanZhang
Street address 7 Science Park Road, ZGC Life Science Park
City Beijing
ZIP/Postal code 102206
Country China
Platforms (1)
GPL21273 HiSeq X Ten (Mus musculus)
Samples (10)
GSM6588081 Con
GSM6588082 SD,6h
GSM6588083 SD,12h
This SubSeries is part of SuperSeries:
GSE213497 Prolonged sleep deprivation induces cytokine storm-like syndrome in mammals
BioProject PRJNA881226

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE213494_featureCounts_RNAseq.txt.gz 440.6 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap