GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE214910 Query DataSets for GSE214910
Status Public on Oct 03, 2023
Title Gene expression profile analysis of the molecular mechanism of HOXD10 regulating epithelial ovarian cancer cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Epithelial ovarian cancer (EOC) is the most common type of ovarian cancer. Although studies have reported that downregulation of HOXD10 expression may contribute to the migration and invasion abilities in EOC, much remains to be fully elucidated. The present study aimed to identify different gene expression profiles of HOXD10 overexpression from the Human OneArray microarray and bioinformatics for the regulation of the progression of EOC cells. Bioinformatics analysis revealed that the pathways of the genes with different expressions were related to oxidative phosphorylation and mitochondrial function. Although the detailed regulatory mechanism between HOXD10 and the targeted oxidative phosphorylation genes is not yet fully understood, the findings of the present provide novel insight on HOXD10-mediated pathways for cancer metabolism, carcinogenesis, and the progression of EOC.
Overall design Examination of HOXD10 in TOV112D
Contributor(s) Hsu CY, Tsai CC, Lo HW, Ou YC, Lin HY, Chen HL, Tsai EM
Citation(s) 38356716
Submission date Oct 06, 2022
Last update date Feb 26, 2024
Contact name ChiaYi Hsu
Organization name Kaohsiung Medical University
Department Graduate Institute of Medicine, College of Medicine
Street address No. 100, Shih-Chung 1
City Kaohsiung
State/province State...
ZIP/Postal code 80708
Country Taiwan
Platforms (1)
GPL21282 Phalanx Human OneArray Ver. 7 Release 1
Samples (4)
GSM6617829 Cell line-Ctrl-rep1
GSM6617830 Cell line-Ctrl-rep 2
GSM6617831 Cell line-HOXD10-rep1
BioProject PRJNA887729

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE214910_RAW.tar 6.1 Mb (http)(custom) TAR (of GPR)
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap