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Series GSE215087 Query DataSets for GSE215087
Status Public on Dec 30, 2022
Title Biochronicity Challenge Study Gene Expression Data
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary A longitudinal human rhinovirus (HRV) challenge study with 19 volunteers was performed at University of Virginia in Sept 2015. The study collected peripheral blood samples 3 times/day over a 8 day time period, where an incoculation with live virus (RV39) was administered on the 4th day (Day 0). The obective was to quantify changes in gene expression induced by the viral challenge.
 
Overall design RNAseq gene expression profiling in whole blood, covering both pre-inoculation (baseline) and post-inoculation time periods. 24 volunteers were recruited into the study, labeled from 01 to 24, of which 18 sucessfully completed the study. Samples were collected from each volunteer in the morning around 8am (AM), in the afternoon around 4pm (PM1) and in the evening around 12pm (PM2).
Web link https://www.nature.com/articles/s41598-022-26081-6
 
Contributor(s) Zhai Y, Hero A, Burke T, Doraiswamy M, Ginsburg G, Henao R, Nix C, Turner RB, Woods CW
Citation(s) 36585416
Submission date Oct 08, 2022
Last update date Jan 11, 2023
Contact name ALFRED Olivier HERO
E-mail(s) hero@umich.edu
Organization name UNIVERSITY OF MICHIGAN
Street address 1301 BEAL AVE
City ANN ARBOR
State/province MI
ZIP/Postal code 48109-2122
Country USA
 
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (395)
GSM6621083 HRV15-002, DayMinus2, PM1
GSM6621084 HRV15-002, DayMinus3, PM2
GSM6621085 HRV15-002, Day3, PM1
Relations
BioProject PRJNA888385

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE215087_gene_TPM.zip 38.2 Mb (ftp)(http) ZIP
GSE215087_genematrix_TPM.csv.gz 37.3 Mb (ftp)(http) CSV
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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