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Series GSE215135 Query DataSets for GSE215135
Status Public on Feb 23, 2024
Title Chromatin attachment to the nuclear matrix represses hypocotyl elongation in Arabidopsis thaliana
Organism Arabidopsis thaliana
Experiment type Other
Expression profiling by high throughput sequencing
Summary The nuclear matrix was identified as a nuclear fraction in eukaryotic cells that offers a supporting scaffold for chromatin. While the structure is known in plant nuclei for decades, the distribution of regions attaching at plant nuclei, and how the nuclear matrix influences chromatin status is largely unkown. Here, we identify novel proteins, FRS7 (FAR1 RELATED SEQUENCE 7) and FRS12, attaching chromatin regions at the nuclear matrix in Arabidopsis thaliana. We found the above two proteins cooperate with AHL22 (AT-hook Motif Nuclear Localized 22) in repress hypocotyl elongation, by recruiting chromatin regions and histone deacetylases to the nuclear matrix and silence the genes. These findings shed light on understanding regulation and roles of the nuclear matrix influence in epigenetic and transcriptional regulation in Arabidopsis.
Overall design We analyze the function of nuclear matrix attachment in transcriptional regulation by RNAseq and MARseq
Contributor(s) Xu L, Zheng S, Jiang H
Citation(s) 38346986
Submission date Oct 10, 2022
Last update date Feb 26, 2024
Contact name Hua Jiang
Phone 049394825875
Organization name Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben
Lab Group of Applied Chromosome Biology
Street address Corrensstra├če 3
City Gatersleben, Stadt Seeland, Germany
ZIP/Postal code 06466
Country Germany
Platforms (1)
GPL26208 Illumina NovaSeq 6000 (Arabidopsis thaliana)
Samples (22)
GSM6622800 Col_MAR_rep1
GSM6622801 Col_MAR_rep2
GSM6622802 sob3-6_MAR_rep1
BioProject PRJNA888981

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE215135_Col_vs_ahl22_gene_count.txt.gz 224.5 Kb (ftp)(http) TXT
GSE215135_Col_vs_frs7frs12_gene_count.txt.gz 227.4 Kb (ftp)(http) TXT
GSE215135_Col_vs_hda15_gene_count.txt.gz 228.2 Kb (ftp)(http) TXT
GSE215135_Col_vs_triple_gene_count.txt.gz 223.1 Kb (ftp)(http) TXT
GSE215135_RAW.tar 91.7 Mb (http)(custom) TAR (of BEDGRAPH)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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