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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jun 07, 2023 |
| Title |
RNA-seq of T cell with/without lycorine treatment in vitro and RNA-seq of T cell in spleen and allograft |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To examine the transcriptomic changes of T cells in response to lycorine, and to compare the transcriptomic changes in spleen T cell and allograft-infiltrating T cell.
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| Overall design |
In vitro experiment, we stimulated mice or human T cells with anti-CD3/anti-CD28 in the presence/absence of lycorine. In vivo experiment, we purified CD4+ and CD8+ T cell from spleen and allograft.
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| Contributor(s) |
Tan X, Chen G |
| Citation(s) |
37013935 |
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| Submission date |
Oct 27, 2022 |
| Last update date |
Jun 07, 2023 |
| Contact name |
Xiaosheng Tan |
| E-mail(s) |
txs900416@hust.edu.cn
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| Phone |
13871387473
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| Organization name |
Huazhong university of science and technology
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| Street address |
#1095, Jiefang Avenu
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| City |
Wuhan |
| ZIP/Postal code |
430030 |
| Country |
China |
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| Platforms (2) |
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| Samples (26)
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| GSM6685568 |
in vitro, lycorine treated splenic CD4+ T, 2 |
| GSM6685569 |
in vitro, control CD4+ T, 1 |
| GSM6685570 |
in vitro, control CD4+ T, 2 |
| GSM6685571 |
in vitro, control CD4+ T, 3 |
| GSM6685572 |
in vitro, control CD4+ T, 4 |
| GSM6685573 |
in vitro, lycorine treated CD4+ T, 1 |
| GSM6685574 |
in vitro, lycorine treated CD4+ T, 2 |
| GSM6685575 |
in vitro, lycorine treated CD4+ T, 3 |
| GSM6685576 |
in vitro, lycorine treated CD4+ T, 4 |
| GSM6685577 |
in vitro, control CD8+ T, 1 |
| GSM6685578 |
in vitro, control CD8+ T, 2 |
| GSM6685579 |
in vitro, control CD8+ T, 3 |
| GSM6685580 |
in vitro, control CD8+ T, 4 |
| GSM6685581 |
in vitro, lycorine treated CD8+ T, 1 |
| GSM6685582 |
in vitro, lycorine treated CD8+ T, 2 |
| GSM6685583 |
in vitro, lycorine treated CD8+ T, 3 |
| GSM6685584 |
in vitro, lycorine treated CD8+ T, 4 |
| GSM6685585 |
in vivo, splenic CD4 |
| GSM6685586 |
in vivo, splenic CD8 |
| GSM6685587 |
in vivo, HT_splenic CD4 |
| GSM6685588 |
in vivo, HT_splenic CD8 |
| GSM6685589 |
in vivo, HT_graft CD4 |
| GSM6685590 |
in vivo, HT_graft CD8 |
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| Relations |
| BioProject |
PRJNA894866 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE216671_HUMAN_All_samples_rpkm.txt.gz |
6.5 Mb |
(ftp)(http) |
TXT |
| GSE216671_IN_VITRO_All_samples_rpkm.txt.gz |
436.3 Kb |
(ftp)(http) |
TXT |
| GSE216671_IN_VIVO_All_samples_rpkm.txt.gz |
588.6 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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