|
| Status |
Public on May 30, 2023 |
| Title |
Steroid receptor coactivator 3 is a key modulator of regulatory T cell–mediated tumor evasionT Cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
SMART-seq analysis is used for single cells or for a small amount of purified total RNA from low number of cells. The goal of this study to compare the quantitative differences between the SRC-3+ and SRC-3-/- Tregs cell transcriptomes.
|
| |
|
| Overall design |
Transcriptome differences between WT and SRC-3KO Tregs explored to explain the anti-tumor effects of SRC-3KO Tregs
|
| Web link |
https://www.pnas.org/doi/10.1073/pnas.2221707120
|
| |
|
| Contributor(s) |
Jain P, Han SJ, Lydon JP, Lonard D, O'Malley BW |
| Citation(s) |
37034717, 37253006 |
| |
| Submission date |
Oct 31, 2022 |
| Last update date |
Sep 08, 2023 |
| Contact name |
Prashi Jain |
| E-mail(s) |
Prashi.Jain@bcm.edu
|
| Organization name |
Baylor college of Medicine
|
| Department |
Molecular and Cellular Biology
|
| Lab |
Bert W. O'Malley
|
| Street address |
1 Baylor Plaza
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA896203 |
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