|
Status |
Public on Jun 30, 2011 |
Title |
Regulation of Human Dendritic Cell Apoptosis and IL-12 Production by MiR-221and MiR-155 through targeting of p27kip1, KPC1 and SOCS1 |
Platform organisms |
Caenorhabditis elegans; Drosophila melanogaster; Danio rerio; Homo sapiens; Mus musculus; Rattus norvegicus |
Sample organism |
Homo sapiens |
Experiment type |
Non-coding RNA profiling by array
|
Summary |
We systematically analyzed miRNA profiling from human monocyte, immature DCs (imDCs) and mature DCs(mDCs) using miRNA microarray . miR-155 and miR-221 expression correlated with p27kip1 accumulation in DCs.
|
|
|
Overall design |
2 replicates for each of 3 cell types (monocyte, imDCs, DCs)
|
|
|
Contributor(s) |
Zeng Y, Lu C, Zhang X, Zhou X |
Citation(s) |
21355095 |
|
Submission date |
May 06, 2010 |
Last update date |
Jun 22, 2012 |
Contact name |
Xiaoxiao Zhang |
E-mail(s) |
zhang688@umn.edu
|
Organization name |
University of Minnesota
|
Street address |
312 Church St. SE
|
City |
Minneapolis |
ZIP/Postal code |
55455 |
Country |
USA |
|
|
Platforms (1) |
GPL9517 |
Multi-species 1.1K miRNA array |
|
Samples (6)
|
|
Relations |
BioProject |
PRJNA127159 |