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| Status |
Public on Mar 06, 2024 |
| Title |
Effects of RYGB on liver health in obese mice. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We investigated the effects of RYGB compared to a sham surgery or caloric restriction on hepatic function. For that, the goals of this study is to identify changes in the liver transcriptome profiling (RNA-seq) that could explain improvements in liver health and function with RYGB compared to other treatment methods.
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| Overall design |
Mice underwent RYGB bariatric surgery, sham surgery, or were weight-matched to the RYGB group via calorie restriction. Mice were euthanized 20 weeks post-surgery and liver tissue was collected.
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| Contributor(s) |
Axelrod CL, Heintz EC, Dantas WS, Kirwan JP |
| Citation(s) |
37731222 |
| |
| Submission date |
Nov 15, 2022 |
| Last update date |
Mar 06, 2024 |
| Contact name |
Jaroslaw Staszkiewicz |
| E-mail(s) |
jaroslaw.staszkiewicz@pbrc.edu
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| Organization name |
Pennington Biomedical Research Center
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| Department |
Genomics Core Facility
|
| Street address |
6400 Perkins Rd
|
| City |
Baton Rouge |
| State/province |
LA |
| ZIP/Postal code |
70810 |
| Country |
USA |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA901944 |
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