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Series GSE221841 Query DataSets for GSE221841
Status Public on Mar 31, 2023
Title Comprehensive analysis of the transcriptome-wide m6A methylation in mouse neural stem cells after hypoxia/reoxygenation
Organism Mus musculus
Experiment type Other
Summary Ischemia-reperfusion injury to the central nervous system (CNS) often causes severe complications. Hypoxia/reoxygenation (H/R) is one of the most common and detrimental internal environmental changes experienced by local cells and is often used to simulate the process of ischemia-reperfusion in vitro. The activation of endogenous neural stem cells (NSCs) is considered a promising therapeutic strategy for nerve repair after injury. However, the specific biological processes and molecular mechanisms of NSC activation remain unclear, and the role of N6-methyladenosine (m6A) methylation modification in this process has not been explored.
Overall design MeRIP-seq was performed on NSCs of control group (n=3) and H/R group (n=3) respectively.
Contributor(s) Fang B, Zhang S, Li Y, Fan Y, Cui K
Citation(s) 38360659
Submission date Dec 28, 2022
Last update date Feb 26, 2024
Contact name Bo Fang
Organization name The First Hospital of China Medical University
Department Department of Anesthesiology
Street address NO.155, North Nanjing Street
City Shenyang
State/province Liaoning
ZIP/Postal code 110001
Country China
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (12)
GSM6900552 NSC, control_input, rep1
GSM6900553 NSC, control_input, rep2
GSM6900554 NSC, control_input, rep3
BioProject PRJNA916478

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE221841_Methylated_RNA_sites.circRNA_Control-A.txt.gz 49.0 Kb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.circRNA_Control-B.txt.gz 38.1 Kb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.circRNA_Control-C.txt.gz 33.5 Kb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.circRNA_HR-A.txt.gz 70.8 Kb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.circRNA_HR-B.txt.gz 58.5 Kb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.circRNA_HR-C.txt.gz 82.8 Kb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.lncRNA_Control-A.txt.gz 146.1 Kb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.lncRNA_Control-B.txt.gz 104.6 Kb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.lncRNA_Control-C.txt.gz 95.8 Kb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.lncRNA_HR-A.txt.gz 247.5 Kb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.lncRNA_HR-B.txt.gz 182.5 Kb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.lncRNA_HR-C.txt.gz 301.1 Kb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.mRNA_Control-A.txt.gz 1.8 Mb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.mRNA_Control-B.txt.gz 1.4 Mb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.mRNA_Control-C.txt.gz 1.2 Mb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.mRNA_HR-A.txt.gz 2.4 Mb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.mRNA_HR-B.txt.gz 1.9 Mb (ftp)(http) TXT
GSE221841_Methylated_RNA_sites.mRNA_HR-C.txt.gz 2.8 Mb (ftp)(http) TXT
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