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Series GSE222041 Query DataSets for GSE222041
Status Public on Sep 06, 2023
Title Identification of potential abnormal methylation modified genes in coronary artery ectasia
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Coronary artery ectasia (CAE) is a rare but easily recognized abnormality of coronary artery anatomy and morphology. Up to now, the pathogenesis of CAE remains unclear.
Firstly, the peripheral venous blood samples of patients with CAE were obtained for the RNA sequencing to identify differentially expressed genes (DEGs), followed by functional analysis. Secondly, DNA methylation profile in CAE was downloaded from the dataset of GSE87016 to identify differentially methylated genes (DMGs). Lastly, after taking interaction genes between DEGs and DMGs, abnormal methylation modified genes were identified.
 
Overall design The aim of this study was to find abnormal methylation modified genes in CAE, which may provide a certain research basis for the pathogenesis of CAE.
 
Contributor(s) Yang X, Zong Y, Zhang Z, Zhao Y, Gao X, Zhang J, Hou Q, Li R, Xiao B
Citation(s) 37662558
Submission date Jan 02, 2023
Last update date Sep 07, 2023
Contact name Xiao Bing
E-mail(s) xiaobing@hb2h.com
Organization name The Second Hospital of Hebei Medical University
Street address No.215, Heping West Road, Shijiazhuang, Hebei, China
City Shijiazhuang
ZIP/Postal code 050000
Country China
 
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (10)
GSM6912190 CAE patient [CAE1]
GSM6912191 CAE patient [CAE2]
GSM6912192 CAE patient [CAE3]
Relations
BioProject PRJNA917424

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE222041_RAW.tar 2.0 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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