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| Status |
Public on Sep 22, 2023 |
| Title |
Transcriptomic profiling of CDCP1 knock-down in human cardiac fibroblasts (HCFs) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To investigate the function of CDCP1 in regulation of HCF proliferation, we cultured primary HCFs and transfected with non-targeting siRNA and CDCP1 siRNAs. Total RNA samples were extracted for RNA-seq to identify transcriptome-wide gene expression changes in the HCFs after CDCP1 knock-down (KD).
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| |
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for HCF cells with and wihout CDCP1 KD.
|
| Web link |
https://www.ahajournals.org/doi/abs/10.1161/CIRCRESAHA.123.323200
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| |
|
| Contributor(s) |
Murthy V, Nguyen TL, Liu D |
| Citation(s) |
37800334 |
| |
| Submission date |
Jan 11, 2023 |
| Last update date |
Oct 09, 2023 |
| Contact name |
Duan Liu |
| E-mail(s) |
liud25@gmail.com, liu.duan@mayo.edu
|
| Organization name |
Mayo Clinic
|
| Department |
MPET
|
| Street address |
200 1st ST SW
|
| City |
Rochester |
| State/province |
MN |
| ZIP/Postal code |
55901 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (4)
|
| GSM6929067 |
HCFs, non-targeting control siRNA, 48 hrs, rep1 |
| GSM6929068 |
HCFs, non-targeting control siRNA, 48 hrs, rep2 |
| GSM6929069 |
HCFs, CDCP1 siRNA, 48 hrs, rep1 |
|
| Relations |
| BioProject |
PRJNA923026 |
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