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Series GSE223630 Query DataSets for GSE223630
Status Public on Oct 05, 2023
Title Mouse Mammary Tumor Models of Various Molecular Subtypes Including Basal-like and Claudin-low TNBC
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Mouse mammary tumors are diverse neoplastic growths originating in the mammary glands of mice and serve as essential models for studying human breast cancer. These tumors can be classified into distinct molecular subtypes, including luminal, basal-like, HER2-enriched, and claudin-low, reflecting the heterogeneity observed in breast cancer. With unique genetic and molecular features, these subtypes are instrumental for understanding the complexities of tumor biology. Here we sequenced the mRNA of 13 treatment-na ve mouse mammary tumor lines for a total of 82 samples.
Overall design Gene expression of 82 individual, untreated mouse mammary tumors from mRNAseq data. At least 2 biological replicates per individual tumor model are included here. The tumor models included in this submission are: 2153, 2208, 2224, 2225, 2250, 2336, 4T1, 9263, E0771, KPB1-A, MMTV-NEU, MMTV-PYMT, and T12.
Contributor(s) Perou CM
Citation(s) 37484164
Submission date Jan 24, 2023
Last update date Jan 04, 2024
Contact name Charles M. Perou
Organization name University of North Carolina at Chapel Hill
Department Professor of Genetics, and Pathology & Laboratory Medicine; Lineberger Comprehensive Cancer Center
Street address 12-044 Lineberger Comprehensive Cancer Center CB# 7295
City Chapel Hill
State/province NC
ZIP/Postal code 27599-7264
Country USA
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (82)
GSM6966348 2153_CP-1977
GSM6966349 2153_CP-2611
GSM6966350 2153_CP-2612
BioProject PRJNA926994

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE223630_gene_counts.txt.gz 4.3 Mb (ftp)(http) TXT
GSE223630_normalized_gene_counts.txt.gz 13.7 Mb (ftp)(http) TXT
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