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Series GSE224401 Query DataSets for GSE224401
Status Public on Mar 03, 2023
Title Effect of ITGB6 induction on transcriptome of breast myoepithelial cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary To investigate the effects of ITGB6 induction of breast myoepithelial cells (1089 and primary myoepithelial cells), we induced expression of ITGB6 utilising the TET-On system for 48 hr.
Overall design Cells (1089 or primary myoepithelial cells) were seeded in 2D and treated with doxycyline to induce overexpression of ITGB6 for 48 hr. 1089 cells were also treated with 10 uM of TGFBRi (SB431542) for 48 hr. Experiments were performed with two biological replicates per sample. Each sample has multiple raw fastq files, corresponding to different sequencing lanes (e.g., L001, L002, L003, L004) and different reads (e.g., R1, R2).
Contributor(s) Gibson SV, Carter EP, Grose RP
Citation(s) 36864079
Submission date Feb 02, 2023
Last update date Jun 14, 2023
Contact name Richard Grose
Organization name Queen Mary University of London
Street address Charterhouse Sq
City London
ZIP/Postal code EC1M 5PZ
Country United Kingdom
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (12)
GSM7021732 1089 myoepithelial cell line (Sample_1_ND1)
GSM7021733 1089 myoepithelial cell line (Sample 2_D1)
GSM7021734 1089 myoepithelial cell line (Sample_3_NDSB1)
BioProject PRJNA930779

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE224401_1089_Myoepithelial_Raw_counts.xlsx 3.1 Mb (ftp)(http) XLSX
GSE224401_Patient_Myoepithelial_Raw_counts.xlsx 1.8 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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