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Series GSE224776 Query DataSets for GSE224776
Status Public on Feb 07, 2023
Title Expression data from chordoma and notochord (microarray)
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Chordoma is a rare malignant tumor thought to originate from embryonic notochord. However, no molecular comparison of chordoma and notochord has been performed to date, leaving the identities of dysregulated pathways unclear.
Absence of a molecular description of a control tissue clouds our understanding of chordoma. Thus, we conducted an unbiased comparison of chordoma and notochord using gene expression profiling to clarify chordoma’s tissue of origin and identify novel drug targets
Overall design RNA was extracted from fresh chordoma tumors after surgical resection using Trizol. RNA from notochord was obtained via laser capture microdissection.
Contributor(s) Halvorsen S
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Submission date Feb 07, 2023
Last update date Feb 13, 2023
Contact name Stefan Halvorsen
Organization name Massachusetts General Hospital
Department Center for Computational and Integrative Biology
Lab Seed Lab
Street address 185 Cambridge Street
City Boston
State/province MA
ZIP/Postal code 02114
Country USA
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (11)
GSM7031937 Chordoma 10
GSM7031938 CH22-2
GSM7031939 CH22-3
This SubSeries is part of SuperSeries:
GSE205458 Expression data from chordoma and notochord
BioProject PRJNA932447

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE224776_RAW.tar 49.3 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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