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Series GSE22837 Query DataSets for GSE22837
Status Public on Dec 22, 2010
Title Identification of differentially methylated regions between placentas and maternal blood cells on chromosome 18
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Comparison of DNA methylation levels of chromosome 18 between placentas and blood cells of pregnant women
Overall design Extracted DNA from 5 cases of placental tissues and 5 cases of maternal blood cell was subjected to MeDIP (methylated DNA immunoprecipitation) and hybridized to Affymetrix GeneChip® Human Tiling 2.0R Array sets. A control without immunoprecipitation (IP) was also processed in parallel with the immunoprecipitated DNA samples. The results were validated with bisulfite sequencing and mass spectrometry-based analysis
Contributor(s) Tsui DW, Lam DY, Lee WS, Leung TY, Lau TK, Lau ET, Tang MH, Akolekar R, Nicolaides KH, Chiu RW, Lo DY, Chim SS
Citation(s) 21152411
Submission date Jul 08, 2010
Last update date Mar 22, 2012
Contact name Yuk Ming Dennis Lo
Organization name The Chinese University of Hong Kong
Department Department of Chemical Pathology
Street address The Prince of Wales Hospital
City Hong Kong
ZIP/Postal code nil
Country China
Platforms (1)
GPL4913 [Hs35b_P04R] Affymetrix Human Tiling 2.0R Set, Array 4
Samples (11)
GSM569413 Placenta MeDIP DNA 1
GSM569414 Placenta MeDIP DNA 2
GSM569415 Placenta MeDIP DNA 3
BioProject PRJNA127895

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource 34.1 Mb (ftp)(http) BAR
GSE22837_RAW.tar 275.0 Mb (http)(custom) TAR (of CEL, TXT)
GSE22837_TAS_placenta_vs_blood_cells_Signal_Log_Ratio_BED.txt.gz 28.5 Kb (ftp)(http) TXT
Processed data are available on Series record

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