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Status |
Public on Feb 12, 2024 |
Title |
UBTF tandem duplication acute myeloid leukemias are sensitive to menin inhibition |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing
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Summary |
This SuperSeries is composed of the SubSeries listed below.
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Overall design |
Refer to individual Series
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Citation(s) |
37890156 |
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Submission date |
Apr 13, 2023 |
Last update date |
Feb 13, 2024 |
Contact name |
Guangchun Song |
Phone |
901-595-5722
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Organization name |
St Jude Children's Research Hospital
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Department |
Pathology
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Lab |
Klco
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Street address |
262 Danny Thomas Place
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City |
Memphis |
State/province |
TN |
ZIP/Postal code |
38105 |
Country |
USA |
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Platforms (1) |
GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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Samples (53)
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GSM7170135 |
RNA-seq in FKBP12 tagged UBTF-TD54 cbCD34+ cells treated with DMSO, C1 |
GSM7170136 |
RNA-seq in FKBP12 tagged UBTF-TD54 cbCD34+ cells treated with DMSO, C2 |
GSM7170137 |
RNA-seq in FKBP12 tagged UBTF-TD54 cbCD34+ cells treated with DMSO, C3 |
GSM7170138 |
RNA-seq in FKBP12 tagged UBTF-TD54 cbCD34+ cells treated with dTAG-13, C4 |
GSM7170139 |
RNA-seq in FKBP12 tagged UBTF-TD54 cbCD34+ cells treated with dTAG-13, C5 |
GSM7170140 |
RNA-seq in FKBP12 tagged UBTF-TD54 cbCD34+ cells treated with dTAG-13, C6 |
GSM7170141 |
RNA-seq of bone marrow cells from UBTF-TD PDX model treated with Veh, R15 |
GSM7170142 |
RNA-seq of bone marrow cells from UBTF-TD PDX model treated with Veh, R16 |
GSM7170143 |
RNA-seq of bone marrow cells from UBTF-TD PDX model treated with Veh, R17 |
GSM7170144 |
RNA-seq of bone marrow cells from UBTF-TD PDX model treated with SNDX, R18 |
GSM7170145 |
RNA-seq of bone marrow cells from UBTF-TD PDX model treated with SNDX, R19 |
GSM7170146 |
RNA-seq of bone marrow cells from UBTF-TD PDX model treated with SNDX, R20 |
GSM7170147 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, IgG |
GSM7170148 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, rep1 HA |
GSM7170149 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, rep 2, HA |
GSM7170150 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, rep 3, HA |
GSM7170151 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, menin |
GSM7170152 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, KMT2A |
GSM7170153 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, POLR2A |
GSM7170154 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, UBTF |
GSM7170155 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, H3K4me3 |
GSM7170156 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, H3K27ac |
GSM7170157 |
cord-blood CD34+ cells, MPC-nHA-UBTF-WT, HA, Day10 |
GSM7170158 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, HA, Day10 |
GSM7170159 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, HA, Day 32 |
GSM7170160 |
cord-blood CD34+ cells, MPC-nHA-UBTF-TD, HA, Day 45 |
GSM7170161 |
cord-blood CD34+ cells, IgG |
GSM7170162 |
cord-blood CD34+ cells, UBTF, rep 1 |
GSM7170163 |
cord-blood CD34+ cells, UBTF, rep 2 |
GSM7170164 |
cord-blood CD34+ cells, UBTF, rep 3 |
GSM7170165 |
UBTF-TD patient-derivied xenograft, UBTF |
GSM7170166 |
UBTF-TD patient-derivied xenograft, KMT2A |
GSM7170167 |
UBTF-TD patient-derivied xenograft, Menin |
GSM7170168 |
KMT2A-rearranged patient-derivied xenograft, UBTF |
GSM7170169 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, IgG |
GSM7170170 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, DMSO, HA, rep1 |
GSM7170171 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, DMSO, Menin, rep1 |
GSM7170172 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, DMSO, KMT2A, rep1 |
GSM7170173 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, dTAG-13-1µM, HA, rep1 |
GSM7170174 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, dTAG-13-1µM, Menin, rep1 |
GSM7170175 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, dTAG-13-1µM, KMT2A, rep1 |
GSM7170176 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, DMSO, HA, rep2 |
GSM7170177 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, DMSO, HA, rep3 |
GSM7170178 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, DMSO, KMT2A, rep2 |
GSM7170179 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, DMSO, KMT2A, rep3 |
GSM7170180 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, dTAG-13-1µM, HA, rep2 |
GSM7170181 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, dTAG-13-1µM, HA, rep3 |
GSM7170182 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, dTAG-13-1µM, KMT2A, rep2 |
GSM7170183 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, dTAG-13-1µM, KMT2A, rep3 |
GSM7170184 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, DMSO, Menin, rep2 |
GSM7170185 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, DMSO, Menin, rep3 |
GSM7170186 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, dTAG-13-1µM, Menin, rep2 |
GSM7170187 |
cord-blood CD34+ cells, MPC-FKBP12-nHA-UBTF-TD, dTAG-13-1µM, Menin, rep3 |
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This SuperSeries is composed of the following SubSeries: |
GSE229663 |
UBTF tandem duplication acute myeloid leukemias are sensitive to menin inhibition [RNA-seq] |
GSE229664 |
UBTF tandem duplication acute myeloid leukemias are sensitive to menin inhibition [Cut&Run] |
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Relations |
BioProject |
PRJNA955252 |
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