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| Status |
Public on May 24, 2024 |
| Title |
Discrimination of direct HIV-1 Tat effects and compensatory reactions of cultured B cells by RNA-seq analysis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We constructed B cell lines with inducible and stable HIV-1 Tat expression and performed RNA sequencing to study the acute and chronic effects of Tat protein.
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| Overall design |
RNA-seq of lymphoblastoid B cell line RPMI8866 with inducible or stable HIV-1 Tat protein expression. Mock RPMI8866 cells and RPMI(Tat-ind) cells before doxycycline treatment were used as controls. Three biological replicates in each group.
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| Contributor(s) |
Valyaeva AA, Tikhomirova MA, Zharikova AA, Penin AA, Potashnikova DM, Musinova YR, Mironov AA, Vassetzky YS, Sheval EV |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
May 25, 2023 |
| Last update date |
Sep 13, 2024 |
| Contact name |
Anna Valyaeva |
| E-mail(s) |
valyaeva.ann@gmail.com
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| Organization name |
Lomonosov Moscow State University
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| Department |
Faculty of Bioengineering and Bioinformatics
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| Street address |
Leninskiye Gory, MSU, 1-73
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| City |
Moscow |
| ZIP/Postal code |
119234 |
| Country |
Russia |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA976359 |
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