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Status |
Public on Feb 06, 2024 |
Title |
ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing
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Summary |
This SuperSeries is composed of the SubSeries listed below.
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Overall design |
Refer to individual Series
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Citation missing |
Has this study been published? Please login to update or notify GEO. |
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Submission date |
Sep 19, 2023 |
Last update date |
Feb 07, 2024 |
Contact name |
Bomiao Hu |
E-mail(s) |
bomiao.hu@yale.edu
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Organization name |
Yale University
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Street address |
310 Cedar Street
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City |
New Haven |
State/province |
CT |
ZIP/Postal code |
06519 |
Country |
USA |
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Platforms (2) |
GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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Samples (64)
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GSM7791001 |
YU-006 PDX, residual |
GSM7791006 |
YU-003 PDX, untreated, rep1 |
GSM7791007 |
YU-003 PDX, untreated, rep2 |
GSM7791008 |
YU-003 PDX, residual, rep1 |
GSM7791009 |
YU-003 PDX, residual, rep2 |
GSM7791010 |
YU-003 PDX, residual, rep3 |
GSM7791011 |
YU-006 PDX, untreated, rep1 |
GSM7791012 |
YU-006 PDX, untreated, rep2 |
GSM7791013 |
YU-006 PDX, residual, rep1 |
GSM7791014 |
YU-006 PDX, residual, rep2 |
GSM7791015 |
YU-006 PDX, residual, rep3 |
GSM7791016 |
YU-030 PDX, untreated, rep1 |
GSM7791017 |
YU-030 PDX, untreated, rep2 |
GSM7791018 |
YU-030 PDX, residual, rep1 |
GSM7791019 |
YU-030 PDX, residual, rep2 |
GSM7791020 |
YU-030 PDX, residual, rep3 |
GSM7791021 |
PC9EV, vehicle, rep1 |
GSM7791022 |
PC9EV, vehicle, rep2 |
GSM7791023 |
PC9EV, vehicle, rep3 |
GSM7791024 |
PC9EV, osimertinib, rep1 |
GSM7791025 |
PC9EV, osimertinib, rep2 |
GSM7791026 |
PC9EV, osimertinib, rep3 |
GSM7791027 |
PC9ASCL1, vehicle, rep1 |
GSM7791028 |
PC9ASCL1, vehicle, rep2 |
GSM7791029 |
PC9ASCL1, vehicle, rep3 |
GSM7791030 |
PC9ASCL1, osimertinib, rep1 |
GSM7791031 |
PC9ASCL1, osimertinib, rep2 |
GSM7791032 |
PC9ASCL1, osimertinib, rep3 |
GSM7791033 |
HCC827EV, vehicle, rep1 |
GSM7791034 |
HCC827EV, vehicle, rep2 |
GSM7791035 |
HCC827EV, vehicle, rep3 |
GSM7791036 |
HCC827EV, osimertinib, rep1 |
GSM7791037 |
HCC827EV, osimertinib, rep2 |
GSM7791038 |
HCC827EV, osimertinib, rep3 |
GSM7791039 |
HCC827ASCL1, vehicle, rep1 |
GSM7791040 |
HCC827ASCL1, vehicle, rep2 |
GSM7791041 |
HCC827ASCL1, vehicle, rep3 |
GSM7791042 |
HCC827ASCL1, osimertinib, rep1 |
GSM7791043 |
HCC827ASCL1, osimertinib, rep2 |
GSM7791044 |
HCC827ASCL1, osimertinib, rep3 |
GSM7791045 |
HCC827ASCL1, persister, rep1 |
GSM7791046 |
HCC827ASCL1, persister, rep2 |
GSM7791047 |
HCC827ASCL1, persister, rep3 |
GSM7791179 |
PC9EV, vehicle, rep1 |
GSM7791180 |
PC9EV, vehicle, rep2 |
GSM7791181 |
PC9EV, osimertinib, rep1 |
GSM7791182 |
PC9EV, osimertinib, rep2 |
GSM7791183 |
PC9ASCL1, vehicle, rep1 |
GSM7791184 |
PC9ASCL1, vehicle, rep2 |
GSM7791185 |
PC9ASCL1, osimertinib, rep1 |
GSM7791186 |
PC9ASCL1, osimertinib, rep2 |
GSM7791187 |
HCC827EV, vehicle, rep1 |
GSM7791188 |
HCC827EV, vehicle, rep2 |
GSM7791189 |
HCC827EV, osimertinib, rep1 |
GSM7791190 |
HCC827EV, osimertinib, rep2 |
GSM7791191 |
HCC827ASCL1, vehicle, rep1 |
GSM7791192 |
HCC827ASCL1, vehicle, rep2 |
GSM7791193 |
HCC827ASCL1, osimertinib, rep1 |
GSM7791194 |
HCC827ASCL1, osimertinib, rep2 |
GSM7791195 |
HCC827ASCL1, persister, rep1 |
GSM7791196 |
HCC827ASCL1, persister, rep2 |
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This SuperSeries is composed of the following SubSeries:
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GSE243562 |
ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts [scRNA-seq] |
GSE243564 |
ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts [PDX RNA-seq] |
GSE243565 |
ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts [Cell Line RNA-seq] |
GSE243568 |
ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts [Cell Line ATAC-seq] |
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Relations |
BioProject |
PRJNA1018938 |
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