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Series GSE2437 Query DataSets for GSE2437
Status Public on Aug 01, 2005
Title Transcriptional changes during neuronal death and replacement in the adult olfactory epithelium
Organism Mus musculus
Experiment type Expression profiling by array
Summary Expression profiling of mRNA abundance in the adult mouse olfactory epithelium during replacement of OSNs forced by the bilateral ablation of the olfactory bulbs. The experiment was done on 6 week old male C57Bl/6 mice. Olfactory epithelium tissue samples were collected on days 1, 5, and 7 after bulbectomy. The cellular processes activated by bulbectomy include apoptosis of mature olfactory sensory neurons, infiltration of macrophages and dendritic cells, stimulation of proliferation of basal cell progenitors, and differentation of new sensory neurons.
Keywords = olfaction
Keywords = apoptosis
Keywords = immune response
Keywords = neurogenesis
Keywords = gene silencing
Keywords = microarray
Keywords = transcription factor
Keywords = spermatogenesis
Keywords: time-course
Contributor(s) Shetty RS, Bose SC, Nickell MD, McIntyre JC, Hardin DH, Harris AM, McClintock TS
Citation(s) 16027002
Submission date Mar 23, 2005
Last update date Feb 18, 2018
Contact name Ranjit S Shetty
Fax 859-323-1070
Organization name University of Kentucky
Department Physiology
Street address 800 Rose Street
City Lexington
State/province KY
ZIP/Postal code 40506
Country USA
Platforms (1)
GPL81 [MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Samples (15)
GSM45675 Untreated,# 1
GSM45676 Untreated,# 2
GSM45677 Untreated,# 3
BioProject PRJNA91903

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE2437_RAW.tar 45.0 Mb (http)(custom) TAR (of CEL, EXP, TXT)

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