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Series GSE244288 Query DataSets for GSE244288
Status Public on Oct 02, 2023
Title FBP1 overexpression in MDA-MB-231 breast cancer cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Fructose 1,6 bisphosphatase the key enzyme of gluconeogenesis has emerged as a potential metabolic tumor suppressor. In breast cancer distinct FBP1 expression levels are found depending on subtype. In MDA-MB-231 FBP1 expression is suppressed. To get more insight into potential functions of FBP1 we introduced a vector to reintroduce expression of FBP1. These experiments are part of a more comprehensive study on expression of FBP1 in breast cancer cells.
Overall design Transfection of MDA-MB231 cells with FBP1 expression vector and empty vector for control.
Contributor(s) Wölfl S, Ghanem A
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Submission date Sep 28, 2023
Last update date Oct 02, 2023
Contact name Stefan Wolfl
Organization name Heidelberg University, Heidelberg, Germany
Department Institute of Pharmacy and Molecular Biotechnology
Lab Pharm. Biology and Bioanalytics
Street address Im Neuenheimer Feld 364
City Heidelberg
ZIP/Postal code D-69120
Country Germany
Platforms (1)
GPL10558 Illumina HumanHT-12 V4.0 expression beadchip
Samples (3)
GSM7812894 FBP1 OE MDA-MB231
GSM7812895 cont1 wt MDA-MB231
GSM7812896 cont2 empty vector MDA-MB231
BioProject PRJNA1022090

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE244288_RAW.tar 31.0 Mb (http)(custom) TAR (of IDAT)
GSE244288_non-normalized_data.txt.gz 1.4 Mb (ftp)(http) TXT

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