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| Status |
Public on Oct 02, 2023 |
| Title |
FBP1 overexpression in MDA-MB-231 breast cancer cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Fructose 1,6 bisphosphatase the key enzyme of gluconeogenesis has emerged as a potential metabolic tumor suppressor. In breast cancer distinct FBP1 expression levels are found depending on subtype. In MDA-MB-231 FBP1 expression is suppressed. To get more insight into potential functions of FBP1 we introduced a vector to reintroduce expression of FBP1. These experiments are part of a more comprehensive study on expression of FBP1 in breast cancer cells.
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| Overall design |
Transfection of MDA-MB231 cells with FBP1 expression vector and empty vector for control.
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| Contributor(s) |
Wölfl S, Ghanem A |
| Citation missing |
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| Submission date |
Sep 28, 2023 |
| Last update date |
Oct 02, 2023 |
| Contact name |
Stefan Wolfl |
| E-mail(s) |
wolfl@uni-hd.de
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| Organization name |
Heidelberg University, Heidelberg, Germany
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| Department |
Institute of Pharmacy and Molecular Biotechnology
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| Lab |
Pharm. Biology and Bioanalytics
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| Street address |
Im Neuenheimer Feld 364
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| City |
Heidelberg |
| ZIP/Postal code |
D-69120 |
| Country |
Germany |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA1022090 |
