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Series GSE248109 Query DataSets for GSE248109
Status Public on Jan 05, 2024
Title 3' RACE-seq of reporter and endogenous LINE-1 mRNA's 3' non-templated ends in 293T and PA-1 cells under permanent (genomic knock-out) or temporal (RNAi) depletions of XRN1, DCP2, (DIS3L2) and control conditions
Organisms Homo sapiens; synthetic construct
Experiment type Other
Summary This SuperSeries is composed of the SubSeries listed below.

Publication: D Janecki, R Sen, N Szóstak, A Kajdasz, M Kordys, K Plawgo, D Pandakov, A Philips, Z Warkocki (2024): LINE-1 mRNA 3’ end dynamics shape its biology and retrotransposition potential. Nucleic Acids Research.
Overall design Refer to individual Series
Citation(s) 38197223
Submission date Nov 17, 2023
Last update date Jan 26, 2024
Contact name Zbigniew Warkocki
Organization name Institute of Bioorganic Chemistry PAS
Street address ul. Z. Noskowskiego 12/14
City Poznan
ZIP/Postal code 61-704
Country Poland
Platforms (2)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
GPL26526 Illumina NovaSeq 6000 (synthetic construct)
Samples (52)
GSM7224135 XRN1 KO, B3
GSM7224136 XRN1 KO, B6
GSM7224137 XRN1 KO, B8
This SuperSeries is composed of the following SubSeries:
GSE230464 3' RACE-seq of reporter LINE-1 and control mRNAs' 3' non-templated ends in 293T 'wild-type', XRN1 KO, DCP2 KO, DCP2 plus XRN1 KO cells
GSE248108 3' RACE-seq of endogenous LINE-1 mRNA's 3' non-templated ends in PA-1 control kd, XRN1 kd, DCP2 kd, and DIS3L2 kd (kd by RNAi for 48h = set 1, or 126h = set 2), and 293T wild-type and XRN1 KO.
BioProject PRJNA1041950

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