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Series GSE248328 Query DataSets for GSE248328
Status Public on Nov 23, 2023
Title Single-cell transcriptome analysis reveals distinct cell populations in dorsal root ganglia and their potential roles in diabetic peripheral neuropathy
Organism Rattus norvegicus
Experiment type Expression profiling by high throughput sequencing
Summary Diabetic peripheral neuropathy (DPN) is the most common form of neuropathy, and have considerable morbidity, which occurs in approximately 50% of diabetic patients. Here, we performed scRNA-seq technology using 10× Genomics sequencing on DRG tissues isolated from control and DPN rats, to identify the cell type composition of DRG, and to reveal the roles of different cell types in mediating DPN.
 
Overall design One sample from bilateral L3-6 DRG tissues of five DPN rats, and one sample from bilateral L3-6 DRG tissues of five normal SD rats.
 
Contributor(s) Guo G, Chen Z
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Submission date Nov 20, 2023
Last update date Nov 24, 2023
Contact name Guojun Guo
E-mail(s) guojun_guo@hust.edu.cn
Organization name Union Hospital of Tongji medical college, Huazhong University of Science & Technology
Department Hand Surgery
Street address 1277# Jiefang Avenue
City Wuhan
State/province Hubei
ZIP/Postal code 430022
Country China
 
Platforms (1)
GPL25947 Illumina NovaSeq 6000 (Rattus norvegicus)
Samples (2)
GSM7911579 DPN
GSM7911580 Control
Relations
BioProject PRJNA1043217

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Supplementary file Size Download File type/resource
GSE248328_RAW.tar 190.4 Mb (http)(custom) TAR (of MTX, TSV)
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Raw data are available in SRA
Processed data provided as supplementary file

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